E cigarettes and cancer Electronic cigarettes (e cigarettes) are sometimes called e cigs, vapes, vape pens, and electronic nicotine delivery systems (ENDS). E cigarettes come in many shapes and sizes. Most e cigarettes contain nicotine. Get the facts about e cigarettes, E Cigarette Smoke Causes Lung Cancer in Mice NYU Langone News Comparing the cancer potencies of emissions from vapourised nicotine products including e cigarettes with those of tobacco smoke Tobacco Control Can vaping cause cancer? The evidence suggests it might.