Frontiers More to Explore: Further Definition of Risk Factors for COPD Differential Gender Difference, Modest Elevation in PM2.5, and e Cigarette Use A new study published in Nicotine & Tobacco Research found that those using e cigarettes alone were more than twice as likely to develop COPD than people who didn't use any tobacco products, Health effects of electronic cigarettes: A review British Columbia Medical Journal The electronic cigarette epidemic Chronic Disease E cigarette use increases risk for developing major respiratory diseases